Paternity tests and kinship analyses

Paternity Test

Why?

  • You are in doubt of your paternity
  • You are uncertain about your genetic relation to your relatives
  • You require a legal expert’s proof for court
  • You would like to clarify issues regarding claims of inheritance.
A paternity test is carried out after a written order has been placed and samples have been taken:
These are usually buccal cells collected with swabs, taken at our laboratory or with the testkit sent to you on request.
 
You can choose between a private and a legally certified expertise as proof for court.
 
For a private report, you come to our lab or a test kit is sent to you on request.
For a legal expertise valid at court, we take the samples by controlling strictly identity of the test persons at our premises. Please make an appointment
Office: +43 1 3684554
Susanne Haas: +43699 13678139

We deliver results within few working days, you will receive a written report.

Paternity test with or without the mother of the child


A maternal sample is (with few exceptions) not mandatory for paternity testing.
There are, however, certain advantages of including the mother:
  • The identity of the child’s sample is secured.
  • The obligatory paternal alleles become evident and we attain a higher probability of paternity, therefore the biostatistical calculation and conclusion is more accurate.
  • Constellations leading to an exclusion of paternity are better defined by identifying the alleles in the child’s pattern that are inherited from the mother.
  • If a close relative of the tested alleged father is considered as potential father as well (for example the brother), we need to be informed and a maternal sample is obligatory

Evaluation of the results


A child that shows one allele corresponding to the mother and the other one to the alleged father at each examined marker position, cannot be excluded in paternity.
We calculate the likelihood based on an exact modelling of hypothesis for the postulated relationship. Our biostatistics software “GenoProof” determines the probability of paternity based on the genotype frequencies in the individual population.
 
A probability of paternity will never be exactly 100% because of the theory of probability and the nature of this calculation, but it will be near to this value and it signifies a proven paternity. In the case of an excluded paternity the value is indeed 100%.
Therefore, the report you receive will confirm your paternity to at least 99.999% (minimum 99.99% without the sample of the mother), then the verbal term "paternity practically proven“ is applied or paternity is excluded.
This is the case when there are four or more non-matches ("exclusion constellations") on different chromosomes. This means that no match can be found in at least four markers positions between the father and child.
The alleged father does not show the expected pattern of the biological father of the child. The exclusion is always confirmed by double analysis of a second sample.
With a total of more than 60 marker systems, we are perfectly equipped to deal with special cases and more difficult calculations.
The more marker systems are analysed, the more information, power of discrimination and higher probability we get.
 
We also take into account the genetic descent of each person (ethnic population) in the calculated probabilities and apply the “step-model” for mutations if necessary.

'Paternity test' without alleged father


In deficiency cases when the sample of one of the persons is missing, e.g. when the alleged father is deceased, this sample can be substituted with samples from the person’s parents.

Other possible indirect paternity tests include:
Grandfather or uncle test (Y-chromosomal = male inheritance),
Grandmother test (X-chromosomal inheritance),
Sibling analyses (X-chromosomal between alleged sisters, Y-chromosomal between alleged brothers).
 
For an indirect maternity test we recommend sequence analysis of mitochondrial DNA.

Confidence

DNA-Analysen GmbH
Formanekgasse 14/1
A-1190 Wien
Tel.: +43 1 368 4554
Fax.: +43 1 367 9694
Wir akzeptieren

Copyright © 2013 by Confidence DNA-Analysen GmbH Alle Rechte vorbehalten.
Die Herstellung von Kopien oder Vervielfältigungen jeglichen Materials in Teilen oder komplett ist ohne vorherige schriftliche Erlaubnis strikt verboten.
created by msdesign